Next Generation Biomarkers:
From Omics to Precision Medicine Van Criekinge, Wim |
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ISBN 13: 9780128143155 ISBN 10: 0128143150 Category: Genetics Edition: 1 Publisher: Elsevier Publication Date: 09/2025 Format: Paperback Status: Not Yet Published Imprint: Academic Press Audience: Professional and scholarly Pages: 400 Weight: 2 Retail Price: 200.00 (Tentative Price May Change) Quantity On Hand: 0 Quantity On Order: 0 |
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Synopsis: Next Generation Biomarkers: From Omics to Precision Medicine offers a clear methodology for successfully discovering and validating biomarkers using next generation sequencing, along with a comprehensive overview of next generation biomarkers currently used in the clinic. With recent advances in genomics and -omics approaches, elaborative molecular profiling is increasingly employed to gain fundamental insights into disease etiology and progression. Through a case-study based approach, the book examines a variety of NGS genomic and omics approaches to biomarker discovery and validation, along with lessons learned from recent studies and clinical trials. Chapters explore common challenges, regulations and strategies for more accurate and efficient development of next generation biomarkers, and NGS approaches, ranging from whole exome sequencing, to whole genome sequencing, epigenomic profiling, transcriptomics, peptidomics, proteomics, liquid biopsy, ethical considerations, and patient empowerment in biomarker development.
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