Acetylcholine in Alzheimer's Disease and Related Dementias:
Zaborszky, Laszlo |
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ISBN 13: 9780128244913 ISBN 10: 0128244917 Category: Research Edition: 1 Publisher: Elsevier Publication Date: 09/2025 Format: Paperback Status: Not Yet Published Imprint: Academic Press Audience: Professional and scholarly Pages: 350 Weight: 2 Retail Price: 150.00 (Tentative Price May Change) Quantity On Hand: 0 Quantity On Order: 0 |
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Synopsis: Acetylcholine in Alzheimer’s Disease and Related Dementias surveys the current state of knowledge on the cholinergic system in rodents, primates and humans. The book's authors discuss aging and AD from system, cellular, molecular and genetic aspects. The book critically evaluates the role of the cholinergic system as it relates to clinical symptoms, therapy and pathogenesis. It follows the history of the cholinergic hypothesis of memory and AD from the seventies/early eighties of the previous century to the current view of disease-modifying roles. The book promotes the idea that the organization of the cholinergic system and its purported homeostatic role may contribute to its higher vulnerability to amyloid pathology of AD.Finally, it discusses current trends of AD prevention from a functional medicine perspective.
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