Targeted Molecular Imaging in Oncology:
Kim, E. Edmund |
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ISBN 13: 9780387950280 ISBN 10: 0387950281 Category: Radiology Edition: 1 Publisher: Springer Copyright: 2001 Format: Cloth LC Call Number: RC270.3.D53 T37 2000 NLM: [DNLM: 1.NEOPLASMS - DIAGNOSIS.QZ 241 T185 2000] Status: Print on Demand Imprint: Springer Affiliation: University of Texas, Houston, TX Audience: Professional Dimensions: 10.0 x 0.5 x 7.01 in Pages: 289 Weight: 3.9 Retail Price: 169.99 Quantity On Hand: 0 |
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Synopsis: Cancer cells dedifferentiate with respect to cell function; their vascularity is more leaky, but perfusion is heterogenerously reduced, and interstitial fluid pressure is high, severely retarding delivery of agents from the blood. Targeted imaging is designed to produce a detectable difference between tissue that is visualized with single photon and positron emission tomography, magnetic resonance imaging, computed tomography, or ultrasonography. This book uniquely reports strategies for the application of molecular targeted imaging agents such as antibodies, peptides, receptors and contrast agents in the biologic grading of tumors, differential diagnosis of tumors, prediction of therapeutic response and monitoring tumor response to treatment. This book also descibes updated information about the imaging of tumor angiogenesis, hypoxia, apoptosis and gene delivery as well as expression in the understanding and utility of tumor molecular biology for better cancer management. |
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