Protein Misfolding in Neurodegenerative Diseases:
Gogia, Neha |
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ISBN 13: 9780443187162 ISBN 10: 0443187169 Category: Genetics Edition: 1 Publisher: Elsevier Publication Date: 03/2025 Format: Paperback Status: Not Yet Published Imprint: Academic Press Audience: Professional and scholarly Pages: 300 Weight: 2 Retail Price: 150.00 (Tentative Price May Change) Quantity On Hand: 0 Quantity On Order: 0 |
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Synopsis: Protein Misfolding in Neurodegenerative Diseases is a comprehensive review of proteome homeostasis in neurons, and in the brain. Beginning with an introduction on factors involved in the formation and aggregation of misfolded proteins, chapters then discuss the precise cellular and molecular mechanisms involved in these processes and their role in neurodegeneration and disease. Additional topics of focus include protein clearance mechanisms like protein quality control, disease-modifiers, molecular druggable targets, novel therapeutics, and emerging techniques that block or delay disease onset or progression. This volume is relevant for researchers working with neurodegenerative diseases, including Alzheimer's disease, Parkinson’s disease, ALS, Creutzfeldt-Jakob disease, and more.
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