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Medicine > Oncology
Overcoming Cancers Resistant to HER-2 Antibodies
Bonavida, Benjamin
ISBN 13: 
9780128164082
ISBN 10: 
0128164085
Category: 
Oncology
Edition: 
1
Publisher: 
Elsevier
Publication Date: 
09/2022
Format: 
Cloth
Status: 
Not Yet Published
Imprint: 
Academic Press
Audience: 
Professional and scholarly
Pages: 
250
Weight: 
2
Retail Price: 
150.00 (Tentative Price May Change)
Quantity On Hand: 
0
Quantity On Order: 
0
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Synopsis:

Overcoming Cancers Resistant to HER-2 Antibodies provides general updated information on the resistance of various human cancers to anti-HER2 therapeutic antibodies. The book also discusses the description of various sensitizing agents that can reverse resistance when used in combination with anti-HER2 antibodies. There have been a lot of reports in which the treatment with anti-HER2 antibodies for various cancers has resulted in clinical responses; however, there have been also subsets of cancer patients who did not respond initially, and several responding patients developed resistance following treatments. Sections cover Lapatinib, Ganetespib, Paclitaxel, Celecoxib, Emantasine, Liposomal Doxorubicin, and Kinase Inhibitors.

This book is a valuable source for cancer researchers, oncologists, pharmacologists and different members of the biomedical field interested in fighting cancer resistance to HER-2 antibodies.



  • Provides a general summary of various sensitizing agents that can work effectively when used in combination with anti-HER2 antibodies to reverse resistance
  • Offers potential underlying mechanisms by which cancer cells are either inherently resistant or become unresponsive to antibody treatment
  • Discusses how to develop new targeted agents to underlie resistance in order to expand research on this field

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