This unique text and reference, the first such book written for graduate-level nursing courses, provides an in-depth foundation for using genetics andgenomic concepts in advanced practice and clinical research. Encompassing state-of-the-art knowledge of the most salient issues in genetics and genomics,it teaches students how to apply understanding of the genome structure and the ethical, legal, and social issues associated with genomics to all aspects ofclinical practice assessment, genetic counseling, patient care, and research.

The text covers the principles of human and molecular genetics, including variations, patterns of inheritance, and multifactorial inheritance. It examinesgene action and expression, cytogenetics, the Human Genome Project, genetics terminology, and basic principles of relevant laboratory methods. The evolvingprinciples of epigenetics, nutrigenomics, and pharmacogenomics in patient care and research are also explored along with their ethical, legal, and socialramifications. Additionally, the text discusses the implications of personalized medicine and direct-to consumer testing in regard to patient care andpractice. Inherited and acquired health conditions are used to illustrate the impact of genetics and genomics on nursing practice and on opportunities forresearch. The text includes numerous case studies and exercises to help understand chromosomal distribution abnormalities along with virtual lab exercisesfor karyotyping and DNA analysis.

Key Features:

• Provides exercises to help understand chromosomal distribution abnormalities
• Includes virtual lab exercises for karyotyping and DNA analysis
• Presents cases to draw pedigrees, and pedigree analysis
• Offers perspectives and case studies regarding ethical, legal, and socioeconomic issues specifically geared to APNs
• Discusses implications of personalized medicine and direct-to-consumer testing