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Book Detail
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Gene Therapy of Cancer:
Methods and Protocols
Walther, Wolfgang
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Affiliation: Max-Delbruck-Center for Molecular Medicine; Berlin, Germany Dimensions: 9.25 x 1.4 x 6.1 in
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Synopsis:
Wolfgang Walther and Ulrike Stein survey the rapidly evolving field of cancer gene therapy and provide a broad array of leading-edge protocols for the delivery of therapeutic genes into tumors. Described in step-by-step fashion and enriched with each author's own practical tips, these readily reproducible methods are currently being widely applied in cancer gene therapy investigations, including immunotherapy and tum or vaccination, suicide gene therapy, antioncogene therapy, and antisense and ribozyme gene therapy. Representative strategies are provided for gene targeting and for viral or nonviral gene delivery in cancer therapy, as well as a significant number of clinical protocols for the development of novel cancer gene therapies.
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