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Book Detail
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Applied Imaging in Systems Pharmacology
Freedman, Immanuel
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Status: Publication Cancelled Audience: Professional and scholarly
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Synopsis:
This book reviews the role of pharmaco-imaging in drug development, in particular to instill the idea that modeling should lead to predictions that a candidate compound can be ruled in or out of an acceptable Clinical Target Product Profile (CTPP) based on clinical go / no-go criteria. Thus, the book drives a candidate drug or biologic’s development via a process that gives a drug company a quantitatively-informed next step. Primarily, the chapters focus on actual drug company products where imaging played a role in the early and advanced development stages. The book has 10-15 examples of drug and biologic development models that use imaging to improve quantitative predictions and, in turn, better decisions.
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